The lack of good plugins is an annoyance. Without Adblock Plus and Noscript, I feel like I'm stepping back into the dark ages of web browsing. (Well, not really the dark ages, but the early advertising age, anyway.) I've grown used to Google Toolbar, and I love having my bookmarks available everywhere via Google Bookmarks, yet Chrome lacks solid support for these plugins. Chrome should make it easy to use the good plugins that already exist for Firefox.
Google Gears doesn't play well with Google Docs. Gears is one of the reasons I use Docs: Docs still works when my network connection breaks. This is important when I'm giving a presentation or collaborating with coworkers--I can't expect my colleagues to wait for the idiot using the cloud office tools to get his network connection back. When I enable Gears on the Docs home page, Gears always complains:
Status: Errors have been foundWhy can't Google's web browser be better integrated with its own products?
An error occurred while updating software. Failed to update software for the applications: Docs Home page, Google Spreadsheets
I'll try Chrome again in another month or so. Until then, I'll stick with Firefox.